Biologics are basically the products which are developed and produced from living organisms like human, plant or animal cells and, of course, microorganisms (bacteria, yeast, etc.). Having no definite structure, biologics are large and complex molecules which undergo sophisticated procedures while being developed and manufactured. Monoclonal antibodies, hormones, enzymes, insulin, etc. can be referred to as biologics.

Generics are simple molecules and exact copies of approved brand drugs. Contrary to biologics, generics are easier to synthesize, purify and manufacture. Drugs such as phenytoin, omeprazole, metformin are common generics. Almost 70 per cent of India’s retail pharmaceutical market is represented by branded generics, which shows their dominance in the country.

Another commonly seen term is biosimilars. As the exact copies of branded drugs are called generics, the highly similar copies of approved biologics are what we call biosimilars. It’s a very generalized definition, however, several crucial factors are considered while defining more precisely.

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